Center for Electron Paramagnetic Resonance Imaging (Halpern Lab)
Center for EPR Imaging in Vivo Physiology
Posts tagged with 'Physical Sciences Collegiate Division'
GrandiLab: Search for Dark Matter with Noble Liquid Technologies
They build specialized, low-background detectors designed to identify rare and low-energy interactions, possibly induced by dark matter interacting with ordinary matter. We have been doing this by contributing to two major experimental efforts in the field: XENON1T (2015-now) and DarkSide-50 (2008-2015), respectively featuring ultrapure xenon and argon as targets for dark matter detection. Both detectors employ the so-called two-phase (gas/liquid) Time Projection Chamber (TPC) technology that allows to simultaneously detect ionization and excitation produced by even tiny energy depositions in the sensitive liquid volume. We are now building XENONnT, an even larger detector featuring with respect to XENOn1T a 4 times larger fiducial mass and a 1/10th background.
Jasmine Nirody
We study the physics of how biological systems interact with their environments, as well as the role of these interactions in shaping organismal morphology and behavior.
We use a range of theoretical and empirical (laboratory + field) techniques to answer questions that sit at the intersection of behavior, biophysics, and evolution.
We work on problems across organismal systems and levels of biological organization. While the underlying mechanisms (and the techniques we use to study them) may vary as we shift our focus from molecular motors to bacteria to animals, the larger questions we are fascinated by remain the same!
- How do biological systems sense and respond to mechanical stresses in complex environments?
- In what environments do adaptive mechanics improve performance?
- How do flexible locomotive strategies affect the evolution of biomechanical structures?
Our research provides ample opportunities for undergraduate engagement. Please email Jasmine at jnirody@uchicago.edu to discuss options!
Kenneth Bader
P.I. willing to mentor undergraduate research volunteers work study students, and students requring pay interested in Biomedical acoustics.
The focus of the Biomedical Acoustics Development and Engineering Research Laboratory (BADER Lab) is the translation of therapeutic ultrasound for non- or minimally invasive treatment of cardiovascular and cancerous disease. Specifically, we utilize acoustic cavitation for combinatorial ablation and enhanced drug delivery treatment strategies of pathologies resistant to standard interventional techniques. To assess bubble activity and the resultant changes in tissue structure, we are developing multi-modal imaging approaches via diagnostic ultrasound and magnetic resonance imaging. Analytic and numerical bubble dynamics models are also utilized to gain insight into the mechanism of action of our therapeutic approaches. Current research topics include:
- Chronic thrombus ablation with histotripsy and thrombolytic drugs
- Passive cavitation and MR imaging to assess histotripsy-induced liquefaction
- In vitro assessment of histotripsy-enhanced drug delivery
- Histotripsy-induced sonochemical reactions for the treatment of cancer
- Numeric and analytic models of bubble dynamics
- Magnetic Resonance-guided transurethral prostate ablation
For more information, visit our laboratory website: baderlab.uchicago.edu
Knowledge Lab
The explosion of digital information offers an unprecedented opportunity to study the dynamics that shape human understanding, investigation and certainty.
Luka Pocivavsek
PI looking for undergraduate research volunteers. My lab is a highly collaborative and interdisciplinary lab that combines the physical sciences, engineering, and surgery. We study aortic pathologies, stability and failure of endovascular repairs, stress focusing phenomena induced by surgical interventions, and interfacial adhesion, surface renewal, and topography.
SurgBioMech Lab
Surgery is anatomy. Anatomy is geometry. Geometry is the heart of mechanics.
SurgBioMech Lab studies the geometry and biomechanics of surgical anatomies and biological interfaces.